Hamburg's Mindpeak using AI to diagnose cancer

Mindpeak has developed the BreastIHC deep learning solution to detect, classify and quantify breast cancer cells. In May, the AI software received its CE-IVD mark. "The CE-IVD mark confirms that BreastIHC meets all essential health and safety requirements outlined in EU directives. That makes us the first company in Germany with such an approval in routine clinical diagnostics in pathology," Faber stressed. The algorithm is now used in ten laboratories including a laboratory chain in the United States, in Poland, and at the Institute of Hematopathology Hamburg.

AI's speed and accuracy can ultimately save lives. The earlier an accurate diagnosis occurs, the more targeted the treatment and the higher the chances of recovery amid increasingly diverse treatment options. Tumors are caused by changing cells. A precise determination of the cancer cell's condition means the most promising therapy can be selected. "BreastIHC recognizes cancer cells and analyses the characteristics of cancer cells," said Faber. Mindpeak has developed an exceptionally robust AI that produces consistently reliable results despite the varying image quality of tissue samples from different laboratories. Crucially, the AI does not have to be adapted to each laboratory.

Breast cancer is one of the most common cancers in Germany followed by lung cancer. Mindpeak now aims to use its algorithm in that field as well. "Our goal is to obtain approval for two additional products this year. An algorithm that identifies and distinguishes lung cancer cells quickly and reliably, and a solution for lymph node metastases," Faber said. "We are developing a platform that will let us adapt our product even faster to different types of cancer. In five years, we want to be able to help pathologists with 80 per cent of their analyses." This gains even more urgency given that the stagnating number of pathologists worldwide.

The Innovationsstarter Fonds Hamburg (IFH) awarded the start-up USD 3 million to develop BreastIHC with APEX Ventures, Nina Capital, Motu Ventures and prominent angel investors. Mindpeak is the first Hamburg-based company to receive combined EIC Accelerator funding from the EU. In August 2020, the start-up obtained an EU grant of EUR 1.4 million and European equity capital of EUR 5 million to expand to other European and U.S. countries.
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